DAPK2 Protein, Human (Active, sf9, His, GST)
DAPK2 Protein, Human (sf9, His, GST) is the recombinant human-derived DAPK2, expressed by Sf9 insect cells , with His, GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
-
Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
DAPK2 Protein, Human (sf9, His, GST) is the recombinant human-derived DAPK2, expressed by Sf9 insect cells , with His, GST labeled tag.
Background
DAPK2 is a calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways regulating cell survival, apoptosis, and autophagy. It controls both caspase-dependent type I apoptotic signals and caspase-independent type II autophagic cell death signals (the latter characterized by autophagic vesicle accumulation), depending on cellular context. DAPK2 acts as a mediator of anoikis and suppresses beta-catenin-dependent anchorage-independent growth in malignant epithelial cells. It may also play a role in granulocytic maturation and regulates granulocytic motility by modulating cell spreading and polarization. by similar: Isoform 2 is not regulated by calmodulin, can phosphorylate MYL9, and induces membrane blebbing and autophagic cell death.
Technical Parameters
-
Species Human
-
Source Sf9 insect cells
-
Tag His;GST
-
Accession
Q9UIK4-1 (F2-S370)
-
Gene ID23604
-
Protein Length
Full Length of Isoform-1
-
Synonyms
DAPK2; MGC119312; Death Associated Protein Kinase 2; DAP-Kinase-Related Protein 1; DRP-1; DAPK2 Protein; Death-Associated Protein Kinase 2; DRP1; DAP Kinase 2
-
AA Sequence
FQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS
-
Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
