GGCT Protein, Human (His)

The GGCT protein is a key player in sulfate assimilation, catalyzing the initial step in the conversion of inorganic sulfate and ATP to adenosine-5'-phosphate sulfate (APS). This activity is essential for the biosynthesis of sulfur-containing amino acids and is essential for cellular sulfur metabolism. GGCT Protein, Human (His) is the recombinant human-derived GGCT protein, expressed by E. coli , with N-6*His labeled tag. The total length of GGCT Protein, Human (His) is 188 a.a., with molecular weight of ~23.0 kDa.

ATP Sulfurylase/MET3 protein serves a pivotal role in sulfate assimilation by catalyzing the initial intracellular reaction that transforms inorganic sulfate and ATP into adenosine-5'-phosphosulfate (APS). This enzymatic activity is a crucial step in the biosynthesis pathway of sulfur-containing amino acids, contributing significantly to cellular sulfur metabolism. By facilitating the activation of sulfate, ATP Sulfurylase/MET3 plays an essential role in ensuring the availability of sulfur for the synthesis of key biomolecules, underscoring its importance in maintaining the cellular pool of sulfur-containing amino acids and supporting fundamental cellular processes.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

O75223 (M1-L188)

79017  [NCBI]

MANSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDEQEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIEDIIKKGETQTL

Approximately 23.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.