GLT25D2 Protein, Human (sf9, His)
GLT25D2 protein is a β-galactosyltransferase that catalyzes the transfer of β-galactose to collagen hydroxylysine residues, thereby affecting the structural diversity and functional properties of collagen.This glycosylation regulates the biochemical and biomechanical properties of collagen, affecting tissue development, maintenance, and repair.GLT25D2 Protein, Human (sf9, His) is the recombinant human-derived GLT25D2 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
GLT25D2 protein is a β-galactosyltransferase that catalyzes the transfer of β-galactose to collagen hydroxylysine residues, thereby affecting the structural diversity and functional properties of collagen.This glycosylation regulates the biochemical and biomechanical properties of collagen, affecting tissue development, maintenance, and repair.GLT25D2 Protein, Human (sf9, His) is the recombinant human-derived GLT25D2 protein, expressed by Sf9 insect cells , with C-His labeled tag.
Background
The GLT25D2 Protein functions as a beta-galactosyltransferase, specifically catalyzing the transfer of beta-galactose to hydroxylysine residues within collagen. This enzymatic activity plays a crucial role in the post-translational modification of collagen, contributing to the structural diversity and functional properties of this essential extracellular matrix protein. By facilitating the glycosylation of hydroxylysine, GLT25D2 participates in the modulation of collagen's biochemical and biomechanical characteristics. Understanding the role of GLT25D2 enhances our comprehension of collagen modification pathways, with potential implications in tissue development, maintenance, and repair. Further exploration of GLT25D2's function holds promise for advancing our knowledge of collagen biology and may contribute to the development of therapeutic strategies targeting collagen-related disorders.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag C-His
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Accession
Q8IYK4 (M1-S622)
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Molecular Construction
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N-term
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GLT25D2 (M1-S622)
Accession # Q8IYK4 -
His
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C-term
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Protein Length
Partial
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Synonyms
COLGALT2; Glycosyltransferase 25 Family Member 2; Prev. C1orf17; Procollagen Galactosyltransferase 2; Prev. GLT25D2; ColGalT 2; KIAA0584; Chromosome 1 Open Reading Frame 17; Glycosyltransferase 25 Domain Containing 2; Procollagen Galactosyltransferase; Co
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AA Sequence
MAARPAATLAWSLLLLSSALLREGCRARFVAERDSEDDGEEPVVFPESPLQSPTVLVAVLARNAAHTLPHFLGCLERLDYPKSRMAIWAATDHNVDNTTEIFREWLKNVQRLYHYVEWRPMDEPESYPDEIGPKHWPTSRFAHVMKLRQAALRTAREKWSDYILFIDVDNFLTNPQTLNLLIAENKTIVAPMLESRGLYSNFWCGITPKGFYKRTPDYVQIREWKRTGCFPVPMVHSTFLIDLRKEASDKLTFYPPHQDYTWTFDDIIVFAFSSRQAGIQMYLCNREHYGYLPIPLKPHQTLQEDIENLIHVQIEAMIDRPPMEPSQYVSVVPKYPDKMGFDEIFMINLKRRKDRRDRMLRTLYEQEIEVKIVEAVDGKALNTSQLKALNIEMLPGYRDPYSSRPLTRGEIGCFLSHYSVWKEVIDRELEKTLVIEDDVRFEHQFKKKLMKLMDNIDQAQLDWELIYIGRKRMQVKEPEKAVPNVANLVEADYSYWTLGYVISLEGAQKLVGANPFGKMLPVDEFLPVMYNKHPVAEYKEYYESRDLKAFSAEPLLIYPTHYTGQPGYLSDTETSTIWDNETVATDWDRTHAWKSRKQSRIYSNAKNTEALPPPTSLDTVPS
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Predicted Molecular Mass
73.8 kDa
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Molecular Weight
Approximately 68 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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