GPR15L Protein, Human (His, Myc)
Based on 1 Customer Validation
GPR15L Protein, Human (His, Myc) is the recombinant human-derived GPR15L protein, expressed by E. coli, with N-10*His & C-Myc tag.
- Species: Human
- Source: E. coli
-
Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Technical Parameters
-
Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
GPR15L Protein, Human (His, Myc) is the recombinant human-derived GPR15L protein, expressed by E. coli, with N-10*His & C-Myc tag.
Background
GPR15L is a highly cationic multifunctional protein. It acts as a chemotactic factor mediating lymphocyte recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. This protein may function as a tumor suppressor, exhibiting growth inhibitory effects on colon cancer cells in conjunction with SUSD2, including induction of G1 cell cycle arrest. GPR15L potentially regulates keratinocyte proliferation. Additionally, by activating Mas-related G protein-coupled receptors (MRGPRs), it contributes to pruritogenesis through activation of itch-selective sensory neurons and mast cell degranulation. by similar: Studies also suggest its significant roles in immune modulation and sensory nerve regulation.
Technical Parameters
-
Species Human
-
Source E. coli
-
Tag N-10*His;C-Myc
-
Accession
Q6UWK7 (K25-V81)
-
Gene ID387695
-
Molecular Construction
-
N-term
-
10*His
-
GPR15L (K25-V81)
Accession # Q6UWK7 -
Myc
-
C-term
-
-
Protein Length
Full Length of Mature Protein
-
Synonyms
GPR15LG; Antimicrobial Peptide With 57 Amino Acid Residues; Prev. C10orf99; Antimicrobial Peptide-57; GPR15L; Protein GPR15 Ligand; AP-57; Protein GPR15LG; CSBF; Protein GPR15L; Colon-Derived SUSD2 Binding Factor; FLJ21763; RLLV1833; Chromosome 10 Open Re
-
AA Sequence
KRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV
-
Predicted Molecular Mass
14 kDa
-
Molecular Weight
Approximately 16 kDa, based on SDS-PAGE under reducing conditions.
-
Structure/Form
Monomer
-
Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, 6% trehalose, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O . For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
-
Data Sheet (235 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz
