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  3. Transferases (EC 2)
  4. GSTT2B Protein, Human (HEK293, His)

GSTT2B Protein, Human (HEK293, His)

Cat. No.: HY-P75802
Handling Instructions

GSTT2B protein, crucial in conjugating reduced glutathione to hydrophobic electrophiles, is essential for cellular detoxification. Its sulfatase activity adds to its multifunctional role in cellular processes. The combined glutathione conjugation and sulfatase function underscore GSTT2B's versatility in handling diverse substrates, emphasizing its significance in cellular detoxification mechanisms. GSTT2B Protein, Human (HEK293, His) is the recombinant human-derived GSTT2B protein, expressed by HEK293 , with C-His labeled tag. The total length of GSTT2B Protein, Human (HEK293, His) is 244 a.a., with molecular weight of ~29 kDa.

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Description

GSTT2B protein, crucial in conjugating reduced glutathione to hydrophobic electrophiles, is essential for cellular detoxification. Its sulfatase activity adds to its multifunctional role in cellular processes. The combined glutathione conjugation and sulfatase function underscore GSTT2B's versatility in handling diverse substrates, emphasizing its significance in cellular detoxification mechanisms. GSTT2B Protein, Human (HEK293, His) is the recombinant human-derived GSTT2B protein, expressed by HEK293 , with C-His labeled tag. The total length of GSTT2B Protein, Human (HEK293, His) is 244 a.a., with molecular weight of ~29 kDa.

Background

GSTT2B protein plays a crucial role in the conjugation of reduced glutathione to a diverse array of hydrophobic electrophiles, both exogenous and endogenous. This enzymatic activity is vital for the detoxification process within cells. Additionally, GSTT2B exhibits sulfatase activity, further contributing to its multifunctional role in cellular processes. The combined activities of glutathione conjugation and sulfatase function highlight the versatility of GSTT2B in handling various substrates and underline its significance in cellular detoxification mechanisms.

Species

Human

Source

HEK293

Tag

C-His

Accession

P0CG29 (M1-P244)

Gene ID

653689

Molecular Construction
N-term
GSTT2B (M1-P244)
Accession # P0CG29
His
C-term
Synonyms
Glutathione S-transferase theta-2B; GST class-theta-2; GSTT2B; GSTT2
Molecular Weight

Approximately 29 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

GSTT2B Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
GSTT2B Protein, Human (HEK293, His)
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HY-P75802
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