KDM4C Protein, Human
KDM4C Protein, Human is the recombinant human-derived JMJD2C, expressed by E. coli , with tag Free labeled tag.
- Species: Human
- Source: E. coli
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Biological Activity
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Product Properties
- Documentation
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Biological Activity
KDM4C Protein, Human is the recombinant human-derived JMJD2C, expressed by E. coli , with tag Free labeled tag.
KDM4C is a histone demethylase that specifically targets 'Lys-9' and 'Lys-36' residues of histone H3, playing a central role in histone code regulation. It does not act on H3 'Lys-4', 'Lys-27', or H4 'Lys-20' residues. The enzyme demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues but shows no activity toward mono- or dimethylated residues. The demethylation reaction produces formaldehyde and succinate. by similar functions also include involvement in chromatin remodeling and gene expression regulation.
Technical Parameters
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Species Human
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Source E. coli
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Tag Tag Free
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Accession
Q9H3R0-1 (M1-K347)
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Gene ID23081
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Protein Length
Partial
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Synonyms
GASC1; JHDM3C; JMJD2C; KIAA0780
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AA Sequence
MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTK
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Predicted Molecular Mass
40.4 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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