KIFC1 Protein, Human (His)
Based on 1 Customer Validation
KIFC1 Protein, a minus end-directed microtubule-dependent motor, is crucial for bipolar spindle formation. It also participates in early endocytic vesicle movement, indicating a role in intracellular transport. Additionally, KIFC1 regulates cilium formation and structure, interacting with NUBP1, NUBP2, and PPP1R42, suggesting potential involvement in processes related to nucleotide binding and protein dephosphorylation. KIFC1 Protein, Human (His) is the recombinant human-derived KIFC1 protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Speicherung:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biologische Aktivität
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biologische Aktivität
KIFC1 Protein, a minus end-directed microtubule-dependent motor, is crucial for bipolar spindle formation. It also participates in early endocytic vesicle movement, indicating a role in intracellular transport. Additionally, KIFC1 regulates cilium formation and structure, interacting with NUBP1, NUBP2, and PPP1R42, suggesting potential involvement in processes related to nucleotide binding and protein dephosphorylation. KIFC1 Protein, Human (His) is the recombinant human-derived KIFC1 protein, expressed by E. coli , with N-6*His labeled tag.
KIFC1 protein, a minus end-directed microtubule-dependent motor, plays a crucial role in bipolar spindle formation, as evidenced by its requirement in this process. Additionally, it is implicated in the movement of early endocytic vesicles, suggesting a potential role in intracellular transport. Furthermore, KIFC1 is involved in the regulation of cilium formation and structure. It interacts with NUBP1 and NUBP2, indicating possible associations with cellular processes related to nucleotide binding. Moreover, its interaction with PPP1R42 suggests involvement in regulatory pathways associated with protein dephosphorylation.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
Q9BW19 (Q305-K673)
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Gene ID3833
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Molecular Construction
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N-term
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6*His
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KIFC1 (Q305-K673)
Accession # Q9BW19 -
C-term
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Protein Length
Partial
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Synonyms
KIFC1; Kinesin-Like Protein KIFC1; Prev. KNSL2; Kinesin-Like 2; HSET; Kinesin-Like Protein; Kinesin-Related Protein HSET; Kinesin Family Member C1; Kinesin-Like Protein 2
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AA Sequence
QELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK
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Predicted Molecular Mass
41.8 kDa
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Reinheit
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
Supplied as a 0.22 μm filtered solution of 50 mM HEPES, pH 7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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