MEF2A Protein, Human (sf9, GST)
MEF2A Protein, Human (sf9, GST) is the recombinant human-derived MEF2A, expressed by Sf9 insect cells , with GST labeled tag. ,
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
MEF2A Protein, Human (sf9, GST) is the recombinant human-derived MEF2A, expressed by Sf9 insect cells , with GST labeled tag. ,
Background
MEF2A is a transcriptional activator that specifically binds to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. It is involved in activating various growth factor- and stress-induced genes and plays critical roles in skeletal and cardiac muscle development, neuronal differentiation, and survival. Through the p38 MAPK signaling pathway, MEF2A regulates cell growth, survival, and apoptosis in muscle-specific or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses NUR77 transcription to promote synaptic differentiation. Additionally, MEF2A associates with chromatin at the ZNF16 promoter.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
Q02078-1 (M1-T507)
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Gene ID4205
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Protein Length
Full Length of Isoform-1
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Synonyms
MEF2A; Myocyte Enhancer Factor 2A Isoform 5; Myocyte Enhancer Factor 2A; Myocyte Enhancer Factor 2A Isoform 3; RSRFC4; Myocyte Enhancer Factor 2A Isoform 4; RSRFC9; Myocyte Enhancer Factor 2A Isoform 1; Serum Response Factor-Like Protein 1; Myocyte Enhancer Factor 2A Isoform 2; Myocyte-Specific Enhancer Factor 2A; Alternative Protein MEF2A; MADS Box Transcription Enhancer Factor 2, Polypeptide A (Myocyte Enhancer Factor 2A), Isoform CRA_d; ADCAD1; MADS Box Transcription Enhancer Factor 2, Polypeptide A (Myocyte Enhancer Factor 2A), Isoform CRA_b; Mef2; MADS Box Transcription Enhancer Factor 2, Polypeptide A (Myocyte Enhancer Factor 2A), Isoform CRA_a; MEF2; MADS Box Transcription Enhancer Factor 2, Polypeptide A (Myocyte Enhancer Factor 2A)
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AA Sequence
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
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Predicted Molecular Mass
88 kDa
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Molecular Weight
Approximately 95 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
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Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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