1. Recombinant Proteins
  2. Viral Proteins
  3. SARS-CoV Proteins
  4. Nucleocapsid Protein NTD domain, Virus (His)

Nucleocapsid Protein NTD domain, Virus (His)

Cat. No.: HY-P7438
Handling Instructions

Nucleocapsid Protein NTD domain, Virus (His) is the N-terminal RNA-binding domain (NTD) of nucleocapsid protein in coronaviruses. Nucleocapsid Protein NTD domain has highly conserved residues in the centre, which is identified as the RNA-binding site[1].

For research use only. We do not sell to patients.

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Nucleocapsid Protein NTD domain, Virus (His) Related Classifications

  • Technical Parameters

  • Properties

  • Documentation

Species

Virus

Source

E. coli

Tag

N-6His

Accession

QHD43423.2

Gene ID

N/A

Synonyms
2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
AA Sequence

N/A

Molecular Weight

Approximately 16.0 kDa

Biological Activity
Data is not available.
Appearance

Solution.

Formulation

Supplied as a 0.2 μm filter solution of PBS, 2 M Urea, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Storage & Stability

Stored at -80°C. It is stable at -20℃ for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Background

Coronaviruses are enveloped viruses with a positive-sense RNA genomeand and has a nucleocapsid of helical symmetry. The Nucleocapsid Protein localize to the cytoplasm and the nucleolus in both virus-infected primary cells and in cells transfected with plasmids that express N protein[1].
Nucleocapsid Protein is a basic protein and is abundant in coronaviruses, which has nonspecific binding activity toward nucleic acids, including ssRNA, ssDNA, and dsDNA. Nucleocapsid Protein is an essential RNA-binding viral protein in human coronavirus (CoV)-infected cells, is required for the replication and transcription of viral RNA. Nucleocapsid Protein NTD domain has highly conserved residues in the centre, which is identified as the RNA-binding site[2].

Documentation
References
  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Nucleocapsid Protein NTD domain, Virus (His)
Cat. No.:
HY-P7438
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