2. Recombinant Proteins
  3. Enzymes & Regulators
  4. PADI4 Protein, Cynomolgus (His)

PADI4 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived PADI4 protein, expressed by E. coli, with N-His tag.

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Descripciòn

PADI4 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived PADI4 protein, expressed by E. coli, with N-His tag.
Background

PADI4 is a hydrolase that converts arginine residues in histones to citrulline. PADI4 promotes tumor progression by up-regulating the cytokine receptor CXCR2. PADI4 can also cause inflammation and immune responses.
Species

Cynomolgus
Source

E. coli
Tag

N-10*His
Accession

A0A2K5USI5 (M1-P663)
Gene ID

/
Protein Length

Full Length
Synonyms
Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase type IV; PADI4; PADI5; PDI5
AA Sequence

MAQGTLIRVTPEQPTHAVCVLGTLTQLDVCSSAPEDCTSFSVNTSPGVVVDIAHSPPAKKKSTGSSTWPLDPGVEVTLTMKAASGSTGDQKVQISYHGPKTPPVKALLYLTGVEISLSADITRTGKVKPTRAVEDKRTWTWGPCGQGAILLVNCDRDNPESSAMDCEDDEVLDSKDLKDMSLMTLSTKTPQDFFTRHTLVLHVARSEMDKVRVFQATRGRLSSRCRVVLGPKQPSHYLMVPGGKHNMDFYVEALAFPDTNFPGLITLTVSMLDTSKLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYVCSIFENEDFLKSVTALAMQARCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGVSGLDSFGNLEVSPPVTVGDKEYPLGRILFGDSCYPSSDSREMHQALQDFLSAQQVQAPVKLYSDWLTVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGDALLFQGIKKKNQQKIKNILSNTTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPIINGRCCLEEKVCSLLEPLGLHCTFINDFYTYHIRHGEVHCGTNVRRKPFSFKWWNMVP

Predicted Molecular Mass
76.6 kDa
Peso molecular

Approximately 76.6 kDa,based on SDS-PAGE under reducing conditions.
Pureza

≥ 95%, as determined by Bis-Tris PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentación
Instrucciones de manejo (2659 KB)

PADI4 Protein, Cynomolgus (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Nombre del producto:
PADI4 Protein, Cynomolgus (His)
Cat. No.:
HY-P703812
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