PRKCI Protein, Human (Active, sf9, GST)
PKC iota proteins are members of the calcium-dependent cell adhesion protein family and play critical roles in cellular interactions. PKC iota acts through a calcium-dependent mechanism and exhibits a preference for homogeneous interacting, connecting cells. PRKCI Protein, Human (sf9, GST) is the recombinant human-derived PRKCI, expressed by Sf9 insect cells, with GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
PKC iota proteins are members of the calcium-dependent cell adhesion protein family and play critical roles in cellular interactions. PKC iota acts through a calcium-dependent mechanism and exhibits a preference for homogeneous interacting, connecting cells. PRKCI Protein, Human (sf9, GST) is the recombinant human-derived PRKCI, expressed by Sf9 insect cells, with GST labeled tag.
Background
Cadherin-17, belonging to the family of calcium-dependent cell adhesion proteins, functions as a pivotal component in cellular interactions. Operating through a calcium-dependent mechanism, cadherins like CDH17 exhibit a propensity for homophilic interactions, preferentially engaging with themselves in connecting cells. This unique property positions cadherins to potentially contribute to the intricate sorting processes of heterogeneous cell types. Specifically, LI-cadherin, a subtype within this family, may play a crucial role in the morphological organization of vital organs such as the liver and intestine. This highlights the diverse and specialized functions that cadherins, including CDH17, fulfill in maintaining tissue integrity and structural organization within specific physiological contexts.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
P41743 (P2-V596)
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Gene ID5584
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Protein Length
Full Length
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Synonyms
PRKCI; PKCI; Prev. DXS1179E; PRKC-Lambda/Iota; Protein Kinase C Iota Type; APKC-Lambda/Iota; NPKC-Iota; Protein Kinase C, Iota; Protein Kinase C Iota; Atypical Protein Kinase C-Lambda/Iota
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AA Sequence
PTQRDSSTMSHTVAGGGSGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCNEVRDMCSFDNEQLFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDDIVRKIDQSEFEGFEYINPLLMSAEECV
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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