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  4. Transferases (EC 2)
  5. PRMT2 Protein, Human (sf9, Flag)

PRMT2 Protein, Human (sf9, Flag) is the recombinant human-derived PRMT2, expressed by Sf9 insect cells , with N-Flag labeled tag. ,

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제품 설명

PRMT2 Protein, Human (sf9, Flag) is the recombinant human-derived PRMT2, expressed by Sf9 insect cells , with N-Flag labeled tag. ,
Background

PRMT2 is an arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4. It acts as a coactivator (with NCOA2) for androgen receptor (AR)-mediated transactivation and (with estrogen) for estrogen receptor (ER)-mediated transactivation. PRMT2 enhances PGR, PPARG, and RARA-mediated transactivation, may inhibit NF-kappa-B transcription, and promotes apoptosis. It represses E2F1 transcriptional activity in an RB1-dependent manner and may be involved in growth regulation.
Species

Human
Source

Sf9 insect cells
Tag

N-Flag
Accession

P55345-1 (A2-R433)
Gene ID

3275
Molecular Construction
N-term
Flag
PRMT2 (A2-R433)
Accession # P55345-1
C-term
Protein Length

Partial
Synonyms
HMT1; HRMT1L1
AA Sequence

ATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQKVGEKVFPIWR

Predicted Molecular Mass
50 kDa
분자량

Approximately 50-52 kDa,based on SDS-PAGE under reducing conditions.
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
각종 서류
Handling Instructions (2659 KB)

PRMT2 Protein, Human (sf9, Flag) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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상품명:
PRMT2 Protein, Human (sf9, Flag)
Cat. No.:
HY-P702893
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