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  4. PRSS2/Trypsin-2 Protein, Human (His)

PRSS2 Protein plays an important role in the metastasis and recurrence of multiple tumor types through its actions of destroying the ECM and activating MMPs. PRSS2/Trypsin-2 Protein, Human (His) is the recombinant mouse-derived PRSS2/Trypsin-2 protein, expressed by E. coli , with N-His labeled tag.

For research use only. We do not sell to patients.

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Description

PRSS2 Protein plays an important role in the metastasis and recurrence of multiple tumor types through its actions of destroying the ECM and activating MMPs. PRSS2/Trypsin-2 Protein, Human (His) is the recombinant mouse-derived PRSS2/Trypsin-2 protein, expressed by E. coli , with N-His labeled tag.
Background

PRSS2 Protein plays an important role in the metastasis and recurrence of multiple tumor types through its actions of destroying the ECM and activating MMPs. PRSS2 enables calcium ion binding activity and serine-type endopeptidase activity. PRSS2 is involved in proteolysis, response to caffeine and response to nicotine.PRSS2 acst upstream of or within digestion[1][2][3].
Species

Human
Source

E. coli
Tag

N-6*His
Accession

P07478 (I24-S247)
Gene ID

5645
Molecular Construction
N-term
6*His
PRSS2 (I24-S247)
Accession # P07478
C-term
Protein Length

Full Length of Mature Protein
Synonyms
Trypsin-2; Anionic trypsinogen; Serine protease 2; Trypsin II; PRSS2; TRY2; TRYP2
AA Sequence

IVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAANS

Predicted Molecular Mass
31.0 kDa
Molecular Weight

Approximately 34 kDa,based on SDS-PAGE under reducing conditions.
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PRSS2/Trypsin-2 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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