RGS1 Protein, Human (His)
RGS1 Protein, Human (His) is the recombinant human-derived RGS1, expressed by E. coli , with His labeled tag. ,
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
RGS1 Protein, Human (His) is the recombinant human-derived RGS1, expressed by E. coli , with His labeled tag. ,
Background
RGS1 regulates G protein-coupled receptor (GPCR) signaling cascades, including pathways downstream of N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). It inhibits signal transduction by enhancing the GTPase activity of G protein alpha subunits, promoting their transition to the inactive GDP-bound state (PubMed:10480894, PubMed:18434541). By similarity, RGS1 also suppresses B cell chemotaxis toward CXCL12.
Technical Parameters
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Species Human
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Source E. coli
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Tag His
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Accession
Q08116-1 (M1-K209)
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Gene ID5996
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Protein Length
Full Length of Isoform-1
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Synonyms
RGS1; Regulator Of G-Protein Signalling 1; Prev. IER1; Early Response Protein 1R20; 1R20; Immediate-Early Response 1, B-Cell Specific; BL34; Epididymis Secretory Protein Li 87; Regulator Of G-Protein Signaling 1; HEL-S-87; IR20; Regulator Of G Protein Sig
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AA Sequence
MRAAAISTPKLDKMPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
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Molecular Weight
Approximately 26 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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