TAGLN2 Protein, Human (HEK293, C-His)

Expressed in HEK 293 cells with a C-His tag, the human isoform of TAGLN2 Protein shares similarity with transgelin, an early marker of differentiated smooth muscle. While its specific function remains unclear, TAGLN2 is proposed as a tumor suppressor. The gene has multiple transcript variants, contributing to its potential roles' complexity. TAGLN2 demonstrates ubiquitous expression, notably in the lung (RPKM 268.8), stomach (RPKM 231.0), and 25 other tissues, suggesting involvement in diverse physiological contexts across multiple organs. TAGLN2 Protein,Human (HEK 293, C-His) is the recombinant human-derived TAGLN2 protein,Human(HEK 293, C-His), expressed by HEK293 , with C-6*His labeled tag. The total length of TAGLN2 Protein,Human (HEK 293, C-His) is 199 a.a., with molecular weight of ~25-30 kDa.

The TAGLN2 Protein, particularly in its human isoform expressed in HEK 293 cells with a C-His tag, shares similarity with transgelin, an early marker of differentiated smooth muscle. While the specific function of TAGLN2 has not been conclusively determined, it is proposed to function as a tumor suppressor. The gene exhibits multiple transcript variants that encode different isoforms, contributing to the complexity of its potential roles. This TAGLN2 protein demonstrates ubiquitous expression, with notable levels detected in the lung (RPKM 268.8), stomach (RPKM 231.0), and 25 other tissues. Its widespread expression pattern suggests involvement in various physiological contexts across multiple organs.

Human

HEK293

C-6*His

P37802/NP_003555 (M1-L199)

8407

MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL

Approximately 25-30 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.