2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Phosphatase
  5. TCTP/TPT1 Protein, Human

TCTP/TPT1 Protein, Human

Cat. No.: HY-P700615
Handling Instructions

TCTP/TPT1 is a multifunctional protein that plays a crucial role in cellular processes by participating in calcium binding and contributing to microtubule stabilization. As a negative regulator, it destabilizes TSC22D1, thereby inhibiting apoptosis. TCTP/TPT1 Protein, Human is the recombinant human-derived TCTP/TPT1 protein, expressed by E. coli , with tag free. The total length of TCTP/TPT1 Protein, Human is 172 a.a., with molecular weight of 19.6 kDa.

For research use only. We do not sell to patients.

Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

TCTP/TPT1 is a multifunctional protein that plays a crucial role in cellular processes by participating in calcium binding and contributing to microtubule stabilization. As a negative regulator, it destabilizes TSC22D1, thereby inhibiting apoptosis. TCTP/TPT1 Protein, Human is the recombinant human-derived TCTP/TPT1 protein, expressed by E. coli , with tag free. The total length of TCTP/TPT1 Protein, Human is 172 a.a., with molecular weight of 19.6 kDa.
Background

TCTP/TPT1, a multifaceted protein, assumes a crucial role in diverse cellular processes. It engages in calcium binding and contributes to microtubule stabilization, indicating its significance in maintaining cellular structure and function. Moreover, TCTP/TPT1 acts as a negative regulator of TSC22D1-mediated apoptosis by interacting with and destabilizing the TSC22D1 protein. The protein forms homodimers and interacts with STEAP3, suggesting its involvement in various protein-protein interactions that orchestrate cellular pathways. The interaction with TSC22D1 highlights its role in modulating apoptotic processes, emphasizing the multifunctional nature of TCTP/TPT1 in cellular homeostasis.
Species

Human
Source

E. coli
Tag

Tag Free
Accession

P13693 (M1-C172)
Gene ID
Molecular Construction
N-term
TCTP (M1-C172)
Accession # P13693
C-term
Synonyms
Translationally-controlled tumor protein; Fortilin; HRF; p23
AA Sequence

MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC

Molecular Weight

19.6 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

TCTP/TPT1 Protein, Human Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TCTP/TPT1 Protein, Human
Cat. No.:
HY-P700615
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.