Transferrin Protein, Pig (HEK293, hFc)
Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, hFc) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.
- Species: Pig
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, hFc) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.
Background
Transferrins, as iron-binding transport proteins, exhibit the capability to bind two Fe(3+) ions, often in conjunction with the binding of an anion, typically bicarbonate. Functionally, transferrin plays a crucial role in transporting iron from sites of absorption and heme degradation to locations dedicated to storage and utilization within the body. Beyond its primary involvement in iron homeostasis, serum transferrin may play an additional role in stimulating cell proliferation. Structured as a monomer, transferrin's versatility underscores its significance in orchestrating the intricate processes of iron transport and cellular regulation, contributing to essential physiological functions within the organism.
Technical Parameters
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Species Pig
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Source HEK293
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Tag C-hFc
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Accession
A0A8D0PY93/NP_001231582.1 (Q22-T715)
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Molecular Construction
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N-term
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Transferrin (Q22-T715)
Accession # A0A8D0PY93/NP_001231582.1 -
hFc
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C-term
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Protein Length
Partial
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Synonyms
TF; Epididymis Secretory Sperm Binding Protein Li 71p; Transferrin; CDNA FLJ54029, Highly Similar To Serotransferrin; Serotransferrin; Transferrin, Isoform CRA_c; Beta-1 Metal-Binding Globulin; TF Protein; Siderophilin; HEL-S-71p; PRO1557; TFQTL1; PRO2086
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AA Sequence
QKTVRWCTISNQEANKCSSFRENMSKAVKNGPLVSCVKKSSYLDCIKAIRDKEADAVTLDAGLVFEAGLAPYNLKPVVAEFYGQKDNPQTHYYAVAVVKKGSNFQWNQLQGKRSCHTGLGRSAGWIIPMGLLYDQLPEPRKPIEKAVASFFSSSCVPCADPVNFPKLCQQCAGKGAEKCACSNHEPYFGYAGAFNCLKEDAGDVAFVKHSTVLENLPDKADRDQYELLCRDNTRRPVDDYENCYLAQVPSHAVVARSVDGQEDSIWELLNQAQEHFGRDKSPDFQLFSSSHGKDLLFKDSANGFLRIPSKMDSSLYLGYQYVTALRNLREEISPDSSKNECKKVRWCAIGHEETQKCDAWSINSGGKIECVSAENTEDCIAKIVKGEADAMSLDGGYIYIAGKCGLVPVLAENYKTEGENCVNTPEKGYLAVAVVKKSSGPDLNWNNLKGKKSCHTAVDRTAGWNIPMGLLYNKINSCKFDQFFGEGCAPGSQRNSSLCALCIGSERAPGRECLANNHERYYGYTGAFRCLVEKGDVAFVKDQVVQQNTDGKNKDDWAKDLKQMDFELLCQNGAREPVDNAENCHLARAPNHAVVARDDKVTCVAEELLKQQAQFGRHVTDCSSSFCMFKSNTKDLLFRDDTQCLARVGKTTYESYLGADYITAVANLRKCSTSKLLEACTFHSAKNPRVETTT
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Predicted Molecular Mass
103 kDa
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Molecular Weight
Approximately 100-110 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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