Tryptase beta-2 Protein, Mouse (HEK293, His)

Tryptase beta-2, a neutral protease abundant in mast cells, plays a key role in innate immunity. As the primary proteolytic enzyme released during mast cell activation, Tryptase beta-2 contributes significantly to immune functions. Its involvement underscores its importance in mediating cellular responses linked to innate immunity, highlighting its role in the intricate defense mechanisms of the immune system. Tryptase beta-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tryptase beta-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Tryptase beta-2 Protein, Mouse (HEK293, His) is 255 a.a., with molecular weight of 32-38 kDa.

Tryptase beta-2, a neutral protease primarily found in mast cells, assumes a significant role in innate immunity. It acts as the major proteolytic enzyme released during the activation-degranulation response of mast cells, contributing to their immune functions. The involvement of Tryptase beta-2 underscores its importance in mediating cellular responses associated with innate immunity, emphasizing its role in the complex and dynamic defense mechanisms of the immune system.

Data is not available.

Mouse

HEK293

C-6*His

P21845 (A22-S276)

17229  [NCBI]

APRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGGADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS

32-38 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 50% glycerin, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.