TXNDC15 Protein, Human (HEK293, His)
TXNDC15 Protein positively regulates ciliary hedgehog signaling, crucial in cellular communication. It actively participates in ciliogenesis, contributing to the structural and functional dynamics of the cellular organelle. TXNDC15 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC15 protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
TXNDC15 Protein positively regulates ciliary hedgehog signaling, crucial in cellular communication. It actively participates in ciliogenesis, contributing to the structural and functional dynamics of the cellular organelle. TXNDC15 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC15 protein, expressed by HEK293 , with C-6*His labeled tag.
Background
TXNDC15 Protein serves as a positive regulator of ciliary hedgehog signaling, playing a crucial role in the intricate network of cellular communication. Additionally, it is actively involved in ciliogenesis, the process of cilium formation, contributing to the structural and functional dynamics of this essential cellular organelle.
Technical Parameters
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Species Human
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Source HEK293
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Tag C-6*His
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Accession
Q96J42-1 (V33-S321)
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Molecular Construction
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N-term
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TXNDC15 (V33-S321)
Accession # Q96J42-1 -
6*His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
TXNDC15; C5orf14; UNQ335; PRO534; Thioredoxin domain-containing protein 15; TMX5; 2310047H23Rik; Thioredoxin Domain Containing 15; BUG; MKS14; Disulfide Isomerase; Chromosome 5 Open Reading Frame 14
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AA Sequence
VEVAEESGRLWSEEQPAHPLQVGAVYLGEEELLHDPMGQDRAAEEANAVLGLDTQGDHMVMLSVIPGEAEDKVSSEPSGVTCGAGGAEDSRCNVRESLFSLDGAGAHFPDREEEYYTEPEVAESDAAPTEDSNNTESLKSPKVNCEERNITGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQIGPLPSTLIKS
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Predicted Molecular Mass
32.5 kDa
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Molecular Weight
Approximately 50-90 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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