UB2Q1 Protein, Human (His, StrepⅡ)
Studies have shown that the UB2Q1 protein plays a key role in cellular processes by catalyzing the covalent attachment of ubiquitin to other proteins. In addition to its ubiquitination function, UB2Q1 may also be involved in female hormonal homeostasis. UB2Q1 Protein, Human (His, Strep) is the recombinant human-derived UB2Q1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
Studies have shown that the UB2Q1 protein plays a key role in cellular processes by catalyzing the covalent attachment of ubiquitin to other proteins. In addition to its ubiquitination function, UB2Q1 may also be involved in female hormonal homeostasis. UB2Q1 Protein, Human (His, Strep) is the recombinant human-derived UB2Q1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.
Background
UB2Q1, also known as ubiquitin-conjugating enzyme E2 Q1, is a protein that catalyzes the covalent attachment of ubiquitin to other proteins, playing a crucial role in ubiquitin-mediated proteolysis. This enzymatic activity is essential for regulating the degradation of specific proteins, influencing various cellular processes. Beyond its ubiquitination function, UB2Q1 may be involved in hormonal homeostasis in females, suggesting potential roles in endocrine regulation. Additionally, UB2Q1 is implicated in the regulation of cell surface expression of B4GALT1, a glycosyltransferase, affecting cell adhesion to laminin and embryoid body formation. These findings underscore UB2Q1's versatility in participating in diverse cellular processes, ranging from ubiquitin-mediated protein degradation to hormonal homeostasis and cell adhesion.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-StrepⅡ;N-6*His
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Accession
Q7Z7E8 (Q2-G422)
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Gene ID55585
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Molecular Construction
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N-term
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StrepⅡ-6*His
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UB2Q1 (Q2-G422)
Accession # Q7Z7E8 -
C-term
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Protein Length
Full Length
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Synonyms
UBE2Q1; Ubiquitin Conjugating Enzyme E2 Q1; UBE2Q; PRO3094; NICE-5; Ubiquitin-Conjugating Enzyme E2 Q1; E2 Ubiquitin-Conjugating Enzyme Q1; Ubiquitin Carrier Protein Q1; Ubiquitin-Protein Ligase Q1; Protein NICE-5; NICE5; Ubiquitin-Conjugating Enzyme E2Q
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AA Sequence
QQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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