SARS-CoV-2 nsp14-IN-4
SARS-CoV-2 nsp14-IN-4 (Compound 12q) is an inhibitor of SARS-CoV-2 nsp14 methyltransferase (IC50=19 nM). SARS-CoV-2 nsp14-IN-4 is non-cytotoxic and cell-permeable. SARS-CoV-2 nsp14-IN-4 is used in COVID-19 research.
For research use only. We do not sell to patients.
- CAS No.: 3049503-97-8
- Formula: C31H27N7O6S
- Molecular Weight:625.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 19 nM (SARS-CoV-2 nsp14 methyltransferase)[1]
SARS-CoV-2 nsp14-IN-4 (5 μM, 60 min) shows excellent stability in microsomes, both mouse and human[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3049503-97-8
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Molecular Weight 625.65
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Formula C31H27N7O6S
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C=C(C#CC3=CC4=CC=CC=C4N=C3)C(C2=NC=N5)=C5N)O[C@@H]1CN(C)S(C6=CC=C(OC)C(C#N)=C6)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)