1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. SB-414796

SB-414796 is a selective, orally active and cross the blood-brain barrier dopamine D3 receptor antagonist with Ki values of 4, 400 nM for D3, D2, respectively.

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SB-414796

SB-414796 Estructura química

No. CAS : 264262-71-7

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Descripciòn

SB-414796 is a selective, orally active and cross the blood-brain barrier dopamine D3 receptor antagonist with Ki values of 4, 400 nM for D3, D2, respectively[1][2].

IC50 & Target[2]

D3 Receptor

4 nM (Ki)

D2 Receptor

400 nM (Ki)

Peso molecular

536.69

Fòrmula

C29H36N4O4S

No. CAS
SMILES

CS(C1=CC2=C(C=C1)CCN(CC2)CC[C@H]3CC[C@@H](CC3)NC(C4=CC=CC(C5=NOC(C)=N5)=C4)=O)(=O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
SB-414796
Cat. No.:
HY-123473
Cantidad:
MCE Japan Authorized Agent: