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TNFRSF11A

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P705490
    RANK/TNFRSF11A Protein, Human (HEK293, mFc)

    Tumor necrosis factor receptor superfamily member 11A; ODFR; CD265; TNFRSF11A; Rank

    		 Human HEK293
  • HY-P72484
    RANK/TNFRSF11A Protein, Human (HEK293, His)

    Tumor necrosis factor receptor superfamily member 11A; ODFR; CD265; TNFRSF11A; Rank

    		 Human HEK293
    RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Human (HEK293, His) has 183 amino acids (I30-P212), produced by HEK293 cells with C-terminal 6*His-tag.
  • HY-P71912
    RANK/TNFRSF11A Protein, Human

    CD 265; CD265; FEO; LOH18CR1; Loss of heterozygosity 18 chromosomal region 1; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB 2; PDB2; RANK; Receptor activator of NF KB; Receptor activator of NF-KB; receptor activator of nuclear factor kappa B; TNF receptor superfamily member 11A; TNFRSF11A; TNR11_HUMAN; TRANCER; Tumor necrosis factor receptor superfamily member 11A NFKB activator; Tumor necrosis factor receptor superfamily member 11A activator of NFKB; Tumor necrosis factor receptor superfamily member 11A

    		 Human E. coli
    RANK/TNFRSF11A protein is the receptor of TNFSF11/RANKL and is critical for RANKL-induced osteoclastogenesis. It interacts with EEIG1 to promote osteoclast formation by promoting NFATC1 transcription and activating PLCG2. RANK/TNFRSF11A Protein, Human is the recombinant human-derived RANK/TNFRSF11A protein, expressed by E. coli , with tag free.
  • HY-P71687
    RANK/TNFRSF11A Protein, Human (His)

    CD265; FEO; TRANCER; Tumor necrosis factor receptor superfamily member 11A NFKB activator

    		 Human E. coli
    RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Human (His) produced by HEK293 cells with N-terminal His-tag.

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