22 Results for "

synchronizing

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "synchronizing" in MCE Product Catalog:

Isotocin acetate
Isotocin acetate
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Cat. No.: HY-P4184A
Synonyms: (Ser4,Ile8)-Oxytocin acetate
Target:  

Endogenous Metabolite Aminopeptidase

Research Areas:  

Neurological Disease

Isotocin acetate is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin acetate exerts biological effects by binding to its homologous Isotocin acetate receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin acetate promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin acetate regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Tambulin
Tambulin
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Cat. No.: HY-N17816
CAS No.: 571-72-2
Category:  

Flavonoids Flavones Rutaceae Plants Zanthoxylum armatum DC.

Target:  

Apoptosis Reactive Oxygen Species (ROS) α-synuclein Succinate Dehydrogenase Bcl-2 Family Caspase

Tambulin is an orally active flavonol compound found in Zanthoxylum armatum. Tambulin can inhibit cell proliferation, induce apoptosis and inhibit ROS production. Tambulin upregulates cleaved caspase-3, cleaved caspase-9, and Bax, downregulates Bcl-2 levels. Tambulin can stimulate glucose-dependent insulin secretion and induce endothelium-independent vasorelaxation. Tambulin binds to succinate dehydrogenase (SDH) (Ki = 11.02 μM) and shows significant ferric reducing power. Tambulin can enhances oxidative stress resistance, reduces, lipofuscin deposits, lipid levels, α-synuclein levels, improves locomotary behavior, and dopamine levels in in age-synchronized L1 hermaphrodite Caenorhabditis elegans models of ageing and Parkinson's disease. Tambulin can be used for the researches of Parkinson's disease, lung squamous cell carcinoma, and diabetes .
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