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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
(1R,2R)-U-50488
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "(1R,2R)-U-50488" in MCE Product Catalog:
17
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
1
1 Cited Publications
Cat. No.: HY-15997
CAS No.: 114528-79-9
Synonyms: (-)-Trans-(1S,2S)-U-50488 hydrochloride
Target:
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) over μ-opioid receptor (MOR) (Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM) .
Target:
Research Areas:
(1R,2R)-U-50488 hydrochloride is the absolute stereochemistry of (±)-U-50488 hydrochloride. (±)-U-50488 hydrochloride is a selective κ opioid receptor (KOR) agonist .
Cat. No.: HY-15997B
CAS No.: 67197-96-0
Synonyms: (±)-Trans-(1R,2R)-U-50488 hydrochloride
Target:
Research Areas:
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist .
Cat. No.: HY-15997C
Synonyms: (±)-Trans-(1R,2R)-U-50488 hydrate hydrochloride
Target:
Research Areas:
(±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrate hydrochloride is a selective κ opioid receptor (KOR) agonist .
Cat. No.: HY-130696
CAS No.: 67198-17-8
Synonyms: (+)-Trans-(1R,2R)-U-50488
Target:
Research Areas:
(+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
Cat. No.: HY-15997A
CAS No.: 114528-81-3
Synonyms: (+)-Trans-(1R,2R)-U-50488 hydrochloride
Target:
Research Areas:
(+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
Cat. No.: HY-130696A
CAS No.: 67198-13-4
Synonyms: (±)-trans-(1R,2R)-U-50488
Target:
Research Areas:
(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy .
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Protocols
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