1 Result for "

(E)-Dosulepin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "(E)-Dosulepin" in MCE Product Catalog:

Cat. No.: HY-165378
CAS No.: 25627-36-5
Synonyms: (E)-Dosulepin hydrochloride; (E)-Dothep hydrochloride
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease

(E)-Dothiepin ((E)-Dosulepin;(E)-Dothep) hydrochloride is an antidepressant agent with sedative/anxiolytic activity. (E)-Dothiepin hydrochloride is an inhibitor preferring of noradrenaline uptake than serotonin uptake. (E)-Dothiepin hydrochloride facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. (E)-Dothiepin hydrochloride is also an antagonist of histamine H1-receptor without cardiotoxicity. (E)-Dothiepin hydrochloride exhibits significant analgesic activity in psychogenic facial pain,idiopathic fibromyalgia syndrome or rheumatoid arthritis .
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