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β-S-ARCA

" in MedChemExpress (MCE) Product Catalog:

2

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2

Oligonucleotides

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-145969
    β-S-ARCA

    3'-O-Me-m7G(5')ppp(5')G

    		 DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) Cancer
    β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA has been applied in researching experimental mRNA-based anticancer vaccines .
    β-S-ARCA
  • HY-145969A
    β-S-ARCA triammonium

    3’-O-Me-m7G(5')ppp(5')G triammonium

    		 DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) Cancer
    β-S-ARCA (3'-O-Me-m7G(5')ppp(5')G) triammonium is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. β-S-ARCA triammonium binds eIF4E via electrostatic interactions between its β-sulfur atom and positively charged Arg and Lys residues in the protein binding site. β-S-ARCA triammonium prevents the decapping by Dcp2, increases the mRNA half-life, enhances cap-dependent translation, and increases protein expression in cells. β-S-ARCA triammonium has been applied in researching experimental mRNA-based anticancer vaccines .
    β-S-ARCA triammonium

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