6 Results for "

KU0059436

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "KU0059436" in MCE Product Catalog:

386
386 Cited Publications
Cat. No.: HY-10162
CAS No.: 763113-22-0
Purity:  99.98%
Synonyms: AZD2281; KU0059436
Target:  

PARP Autophagy Mitophagy

Research Areas:  

Cancer

Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator. Olaparib cannot cross the intact blood-brain barrier (BBB) .
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1
1 Cited Publications
Cat. No.: HY-10162R
CAS No.: 763113-22-0
Synonyms: AZD2281 (Standard); KU0059436 (Standard)
Research Areas:  

Cancer

Olaparib (Standard) is the analytical standard of Olaparib. This product is intended for research and analytical applications. Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
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Cat. No.: HY-10162S
CAS No.: 2143107-56-4
Purity:  ≥99.0%
Synonyms: AZD2281-d5; KU0059436-d5
Olaparib-d5 (AZD2281-d5) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
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Cat. No.: HY-10162S1
Purity:  99.57%
Synonyms: AZD2281-d8; KU0059436-d8
Olaparib-d8 (AZD2281-d8) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
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Cat. No.: HY-10162S3
CAS No.: 2143107-55-3
Purity:  98.59%
Synonyms: AZD2281-d4-1; KU0059436-d4-1
Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
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Cat. No.: HY-10162S4
Synonyms: AZD2281-d4-2; KU0059436-d4-2
Olaparib-d4-2 is the deuterium labeled Olaparib (HY-10162). Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator. Olaparib cannot cross the intact blood-brain barrier (BBB) .
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