1 Result for "

1-Octyl 2-oxopentanedioate

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1-Octyl 2-oxopentanedioate" in MCE Product Catalog:

Cat. No.: HY-114333
CAS No.: 876150-14-0
Synonyms: 1-Octyl 2-oxopentanedioate
Research Areas:  

Metabolic Disease Cancer

Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD [1].
loading...
    loading...