Octyl-α-ketoglutarate

(Synonyms: 1-Octyl 2-oxopentanedioate)
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Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 876150-14-0
  • Formula: C13H22O5
  • Molecular Weight:258.31
  • Storage:

    Solution, -20°C, 2 years

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All HIF/HIF Prolyl-Hydroxylase Isoforms

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