876150-14-0

Octyl-α-ketoglutarate Chemical Structure
876150-14-0

Chemical Structure

Octyl-α-ketoglutarate

Synonym(s): 1-Octyl 2-oxopentanedioate

  • CAS No.: 876150-14-0
  • Formula:C13H22O5
  • Molecular Weight:258.31

IUPAC Name: 5-(octyloxy)-4,5-dioxopentanoic acid

InChIKey: QNFIHKFBQFJVKV-UHFFFAOYSA-N

SMILES: O=C(OCCCCCCCC)C(CCC(O)=O)=O

Biological Activity: Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD[1].
The product specifications provided below refer solely to the active content of Octyl-α-ketoglutarate.

Cat. No. Product Name Purity Description Pricing
HY-114333 		Octyl-α-ketoglutarate 99.9% Octyl-α-ketoglutarate (1-Octyl 2-oxopentanedioate) is a stable, cell-permeable form of α-ketoglutarate which accumulates rapidly in HEK293 cells with a dysfunctional tricarboxylic acid (TCA) cycle, stimulating prolyl hydroxylase (PHD) activity. In addition, Octyl-α-ketoglutarate competitively blocks succinate- or fumarate-mediated inhibition of PHD.
The product specifications provided below refer solely to the active content of Octyl-α-ketoglutarate.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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