2 Results for "

1557268-90-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1557268-90-2" in MCE Product Catalog:

Cat. No.: HY-183397
CAS No.: 1557268-90-2
Synonyms: Abivertinib dihydrochloride; AC0010 dihydrochloride
Target:  

EGFR Btk Apoptosis

Research Areas:  

Cancer

Avitinib (Abivertinib) dihydrochloride is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib dihydrochloride is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib dihydrochloride shows anticancer effects .
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4
4 Cited Publications
Cat. No.: HY-19816
CAS No.: 1557267-42-1
Synonyms: Abivertinib; AC0010
Target:  

EGFR Btk Apoptosis

Research Areas:  

Cancer

Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects .
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