4 Results for "

155974-00-8

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "155974-00-8" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0162
CAS No.: 155974-00-8
Target:  

HCN Channel

Research Areas:  

Cardiovascular Disease Cancer

Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity .
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3
3 Cited Publications
Cat. No.: HY-B0162A
CAS No.: 148849-67-6
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity .
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Cat. No.: HY-B0162S
CAS No.: 2070009-62-8
Ivabradine-d6 is the deuterium labeled Ivabradine . Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity .
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Cat. No.: HY-B0162AS
CAS No.: 2070009-63-9
Ivabradine-d6 hydrochloride is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.
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