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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
16S Rrna
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "16S Rrna" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: N3-Methyluridine
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Cat. No.: HY-N11857
CAS No.: 25876-11-3
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Cat. No.: HY-E71201
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16S rRNA Pseudouridine516 synthase (EC 5.4.99.19) is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
Cat. No.: HY-E71200M
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16S rRNA (guanine966-N2)-Methyltransferase (EC 2.1.1.171) efficiently methylates guanine966 of the assembled 30S subunits in vitro. Protein-free 16S rRNA is not a substrate for RsmD. The enzyme specifically methylates guanine966 at N2 in 16S rRNA.
Cat. No.: HY-E71200E
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16S rRNA (cytosine1407-C5)-Methyltransferase (EC 2.1.1.178) specifically methylates cytosine1407 at C5 in 16S rRNA.
Cat. No.: HY-E71200H
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16S rRNA (cytosine967-C5)-Methyltransferase (EC 2.1.1.176) specifically methylates cytosine967 at C5 in 16S rRNA.
Cat. No.: HY-E71200K
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16S rRNA (guanine1516-N2)-Methyltransferase (EC 2.1.1.242) specifically methylates guanine1516 at N2 in 16S rRNA.
Cat. No.: HY-E71200L
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16S rRNA (guanine527-N7)-Methyltransferase (EC 2.1.1.170) specifically methylates guanine527 at N7 in 16S rRNA.
Cat. No.: HY-E71200N
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16S rRNA (uracil1498-N3)-methyltransferase (EC 2.1.1.193) specifically methylates uracil 1498 at the N3 position in 16S rRNA.
Cat. No.: HY-E71200I
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16S rRNA (guanine1207-N2)-Methyltransferase (EC 2.1.1.172) reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA. The enzyme specifically methylates guanine1207 at N2 in 16S rRNA.
Cat. No.: HY-E71200C
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16S rRNA (cytidine1409-2'-O)-Methyltransferase (EC 2.1.1.227) from Mycobacterium tuberculosis 2'-O-methylates cytidine1409 in helix 44 of 16S rRNA and cytidine1920 in helix 69 of 23S rRNA.
Cat. No.: HY-E71200
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16S rRNA (adenine1408-N1)-Methyltransferase (EC 2.1.1.180) provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N1-methylation at position adenine1408.
Cat. No.: HY-E71200J
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16S rRNA (guanine1405-N7)-Methyltransferase (EC 2.1.1.179) specifically methylates guanine1405 at N7 in 16S rRNA, thereby rendering the ribosome resistant to 4,6-disubstituted deoxystreptamine aminoglycosides, which include gentamicins and kanamycins.
Cat. No.: HY-E71200B
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16S rRNA (cytidine1402-2'-O)-Methyltransferase (EC 2.1.1.198) catalyses the 2'-O-methylation of cytidine1402 and RsmH (EC 2.1.1.199) catalyses the N4-methylation of cytidine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
Cat. No.: HY-E71200D
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16S rRNA (cytosine1402-N4)-Methyltransferase (EC 2.1.1.199) catalyses the N4-methylation of cytosine1402 andRsmI (EC 2.1.1.198) catalyses the 2'-O-methylation of cytosine1402 in 16S rRNA. Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
Cat. No.: HY-E71200A
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KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin.
Cat. No.: HY-175228
RNA MTase-IN-1 (Compound 47) is a RNA methyltransferase (RNA MTase) inhibitor with an IC50 of 68 μM for 16S rRNA (m 1A1408) methyltransferase (NpmA). RNA MTase-IN-1 has a significant inhibitory activity against pathogen-associated aminoglycoside-resistance. RNA MTase-IN-1 can be used for resistant bacterial infections research .
Cat. No.: HY-16955
CAS No.: 1154757-24-0
Synonyms: ACHN 490
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Plazomicin (ACHN 490) is a semi-synthetic aminoglycoside Antibiotic. Plazomicin acts as a substrate for Aminoglycoside acetyltransferase and Aminoglycoside phosphotransferase. Plazomicin is not modified by various common aminoglycoside-modifying enzymes. Plazomicin selectively inhibits MATE2-K. Plazomicin exhibits activity against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales .
Cat. No.: HY-P11730
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
