25876-11-3
25876-11-3
Chemical Structure
Gentamicin C2
- CAS No.: 25876-11-3
- Formula:C20H41N5O7
- Molecular Weight:463.57
InChIKey: XUFIWSHGXVLULG-IDLVJFIQSA-N
SMILES: O[C@@H]([C@@H]1O[C@H]([C@@H](CC2)N)O[C@]2([H])[C@H](N)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@@H](OC[C@@]3(O)C)[C@@H]([C@H]3NC)O
Biological Activity: Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections[1][2][3].
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Gentamicin C2 | Gentamicin C2 is an aminoglycoside antibiotic with broad-spectrum bactericidal activity, selectively binding to the bacterial 16S rRNA A-site. Gentamicin C2 interferes with protein synthesis initiation and translation fidelity to exert bactericidal effects. Gentamicin C2 can be used for the research of bacterial infections. | |||||||||||||||||||||
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References
- [1]. Gu Y, et al. Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex. Chembiochem. 2015;16(13):1933-1942. [Content Brief]
- [2]. Isoherranen N, et al. Pharmacokinetics of gentamicin C(1), C(1a), and C(2) in beagles after a single intravenous dose. Antimicrob Agents Chemother. 2000 Jun;44(6):1443-7. [Content Brief]
