1 Result for "

1807758-81-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1807758-81-1" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-135899
CAS No.: 1807758-81-1
Purity:  98.81%
Target:  

Sirtuin Apoptosis

Research Areas:  

Cancer

SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway. .
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