1807758-81-1

SIRT7 inhibitor 97491 Chemical Structure
1807758-81-1

Chemical Structure

SIRT7 inhibitor 97491

  • CAS No.: 1807758-81-1
  • Formula:C15H12ClN3O
  • Molecular Weight:285.73

IUPAC Name: N1-(5-(4-chlorophenyl)oxazol-2-yl)benzene-1,3-diamine

InChIKey: RMRVZWMKRCLSFX-UHFFFAOYSA-N

SMILES: NC1=CC(NC2=NC=C(C3=CC=C(Cl)C=C3)O2)=CC=C1

Biological Activity: SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.[1].

Cat. No. Product Name Purity Description Pricing
HY-135899 		SIRT7 inhibitor 97491 98.81% SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway..
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