1 Result for "

1906915-49-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1906915-49-8" in MCE Product Catalog:

Cat. No.: HY-156242
CAS No.: 1906915-49-8
Research Areas:  

Cancer

BQZ-485 is a GDI2 inhibitor and a paraptosis inducer with antitumor activity. BQZ-485 binds to the Rab-binding platform domain of GDI2, disrupts the interaction between GDI2 and Rab1A, and impairs the membrane recycling of Rab1A. BQZ-485 blocks vesicle trafficking from the endoplasmic reticulum to the Golgi apparatus, and induces endoplasmic reticulum expansion, endoplasmic reticulum fusion, endoplasmic reticulum stress, unfolded protein response and cytoplasmic vacuolization. BQZ-485 is applicable to pancreatic cancer-related research .
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