1 Result for "

24506-68-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "24506-68-1" in MCE Product Catalog:

Cat. No.: HY-167825
CAS No.: 24506-68-1
Barakol is an anticancer and anxiolytic agent identified in Cassia siamea. Barakol inhibits MMP-3 activity and enhances the cytotoxicity and antimetastatic effects of Doxorubicin (HY-15142) against cancer cells. Barakol induces apoptosis via reactive oxygen species (ROS) production, upregulation of the Bax/Bcl-2 protein ratio, and activation of caspase-9. Barakol exerts anxiolytic activity with diazepam-like effects, increases spontaneous longitudinal smooth muscle contraction of rat ileum in a concentration-dependent manner (EC50 = 0.3 mM), and inhibits norepinephrine-induced contraction suppression. Barakol can be used in research related to anxiety, intestinal motility, and neuroblastoma .
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