2 Results for "

25222-43-9

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "25222-43-9" in MCE Product Catalog:

4-Hydroxymethylpyrazole
4-Hydroxymethylpyrazole
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Cat. No.: HY-33914
CAS No.: 25222-43-9
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Drug Metabolite

4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876) produced through hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, but its inhibition constant is significantly higher than that of Fomepizole, rendering its in vivo impact negligible .
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4-Hydroxymethylpyrazole (Standard)
4-Hydroxymethylpyrazole (Standard)
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Cat. No.: HY-33914R
CAS No.: 25222-43-9
Category:  

Natural Products Endogenous metabolite

Target:  

Drug Metabolite Reference Standards

4-Hydroxymethylpyrazole (Standard) is an analytical standard for 4-Hydroxymethylpyrazole (HY-33914). This product is intended for research and analytical applications. 4-Hydroxymethylpyrazole is the primary metabolite of fomepizole (HY-B0876) via hepatic oxidative metabolism. 4-Hydroxymethylpyrazole exhibits a plasma concentration that is positively correlated with the administered dosage of Fomepizole, and it demonstrates a relatively short half-life. 4-Hydroxymethylpyrazole inhibits alcohol dehydrogenase (ADH) in humans and monkeys, but the inhibition constant is much higher than that of fomepizole and is therefore negligible in vivo
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