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2891469-81-9

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1 Results for "2891469-81-9" in MCE Product Catalog:

NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)
NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)
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Cat. No.: HY-P3347
CAS No.: 2891469-81-9
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) (compound 40), a macrocyclic analogue of Ape13, is a potent APJ agonist (Ki=5.7 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) exhibits a favorable Gα12-biased signaling and an increased in vivo half-life .
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