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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
3'-poly(A) tail
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "3'-poly(A) tail" in MCE Product Catalog:
Cat. No.: HY-174497
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
Cat. No.: HY-W416291
CAS No.: 26763-19-9
Synonyms: poly(A)
Polyadenylic acid potassium (Poly(A)) is a polyribonucleotide. Polyadenylic acid potassium constitutes the 3'-poly(A) tail of eukaryotic mRNAs, governing mRNA maturation, stability, and translation initiation. Polyadenylic acid potassium serves as a target for studying nucleic acid structure-function relationships, with small molecules binding its tail influencing mRNA function and protein production. Polyadenylic acid (potassium) can be used for the research of cancer .
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Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end. Poly(A) polymerase increases RNA stability and increases mRNA translation efficiency in eukaryotic cells. Poly(A) polymerase has high tailing efficiency and can add 20-200 A bases to the 3' end of RNA .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
