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3008535-20-1

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1 Results for "3008535-20-1" in MCE Product Catalog:

Cat. No.: HY-161505
CAS No.: 3008535-20-1
Target:  

Transthyretin (TTR)

Research Areas:  

Others

Transthyretin-IN-3 (compound 6) is a designed benzofuran analogue. Transthyretin-IN-3 selectively binds to plasma transthyretin (TTR) to inhibit Amyloid aggregation (IC50=5.0±0.2 μM). Transthyretin-IN-3 can bind to TTR's thyroxine binding site specifically by carrying chlorine substituents at specific locations in its structure. This binding can prevent TTR tetramers from dissociating into unstable monomers .
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