1 Result for "

3008543-34-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3008543-34-5" in MCE Product Catalog:

Cat. No.: HY-157480
CAS No.: 3008543-34-5
Purity:  99.43%
Target:  

EGFR Aurora Kinase

Research Areas:  

Cancer

EGFR/AURKB-IN-1 (compound 7) is a dual-targeted EGFR/AURKB inhibitor, and inhibits the phpsphorylations of L858R EGFR and AURKB with IC50s of 0.07 and 1.1, respectively. EGFR/AURKB-IN-1 occupies the hydrophobic region I or the αC-helix out pocket of EGFR and the back pocket of AURKB, inhibiting the growth, division and metastasis of tumor cells, thus can be used for cancer research .
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