1 Result for "

3052303-53-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3052303-53-1" in MCE Product Catalog:

Cat. No.: HY-149393
CAS No.: 3052303-53-1
Purity:  95.98%
Research Areas:  

Cancer

RIPK3-IN-3 (compound 20) is a selective inhibitor of RIP kinase RIPK3 (IC50=10 nM). RIPK3 mediates the phosphorylation of Mixed Lineage Kinase (MLKL) and causes necroptosis, while RIPK3-IN-3 inhibits p-MLKL oligomerization and thereby inhibits necroptosis. RIPK3-IN-3 also downregulates CXCL5 secretion and inhibits AsPC-1 cell migration and invasion .
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