1 Result for "

3056618-93-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3056618-93-7" in MCE Product Catalog:

Cat. No.: HY-181652
CAS No.: 3056618-93-7
Target:  

PPAR

Research Areas:  

Endocrinology

PPARδ agonist 13 is a potent, selective and orally active PPARδ agonist with an EC50 values of 0.50 nM. PPARδ agonist 13 binds to the PPARδ ligand-binding pocket and upregulates PPARδ target gene expression. PPARδ agonist 13 inhibits renal fibroblast activation, restores fatty acid oxidation, and attenuates TGF-β1-induced renal fibroblast activation. PPARδ agonist 13 exhibits anti-renal fibrosis effects in a mouse model of unilateral ureteral obstruction. PPARδ agonist 13 can be used for the research of renal fibrosis .
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