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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
5F
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "5F" in MCE Product Catalog:
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4 Cited Publications
CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity .
Art. -Nr.: HY-P99232
CAS. Nr.: 1497400-26-6
Synonyms: 5F9 Monoclonal antibody; TAK-164 Antibody
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Synonyms: NSC-703786
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5F-203 (NSC-703786) is a cytotoxic molecule that forms DNA adducts and cell cycle arrest. 5F-203 induces aryl hydrocarbon receptor (AhR) signaling and elevates expression of CYP1A1. 5F-203 also increases the levels of reactive oxygen species as well as activates JNK, ERK, and p38 .
Art. -Nr.: HY-132226
CAS. Nr.: 2468780-76-7
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Desamino lenalidomide-5-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-F can be linked to a target protein ligand via a linker to form a PROTAC.
Art. -Nr.: HY-P1840
CAS. Nr.: 142846-71-7
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Art. -Nr.: HY-W355129
CAS. Nr.: 77500-04-0
Synonyms: 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2
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MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors .
Art. -Nr.: HY-P5722
CAS. Nr.: 908065-90-7
Art. -Nr.: HY-RS01202
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ATP5F1A Human Pre-designed siRNA Set A contains three designed siRNAs for ATP5F1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-175216
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Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 is a drug-linker conjugate for ADC. Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 can be used for synthesis of ADCs .
Art. -Nr.: HY-RS10907
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POU5F1 Human Pre-designed siRNA Set A contains three designed siRNAs for POU5F1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS10908
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Pou5f1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pou5f1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS01203
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ATP5F1B Human Pre-designed siRNA Set A contains three designed siRNAs for ATP5F1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS01204
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ATP5F1C Human Pre-designed siRNA Set A contains three designed siRNAs for ATP5F1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS19833
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Atp5f1b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atp5f1b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-152083
CAS. Nr.: 791838-63-6
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DENV-IN-9 (Compound 5f) is a DENV2 inhibitor with an EC50 of 0.88 μM .
Art. -Nr.: HY-W281364
CAS. Nr.: 76180-96-6
2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .
Art. -Nr.: HY-134178A
Synonyms: 5-Fluorouridine-5'-triphosphate trisodium
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5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
Art. -Nr.: HY-124421R
CAS. Nr.: 260443-89-8
Synonyms: NSC-703786 (Standard)
Forschungsgebiete:
5F-203 (Standard) is the analytical standard of 5F-203. This product is intended for research and analytical applications. 5F-203 (NSC-703786) is a cytotoxic molecule that forms DNA adducts and cell cycle arrest. 5F-203 induces aryl hydrocarbon receptor (AhR) signaling and elevates expression of CYP1A1. 5F-203 also increases the levels of reactive oxygen species as well as activates JNK, ERK, and p38 .
Art. -Nr.: HY-178922
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CAI/II-IN-13 (Compound 5f) is a CAI/II inhibitor, with IC50 values of 309.16 nM for hCA I and 267.27 nM for hCA II. CAI/II-IN-13 exhibits potent and selective antiproliferative activity against A549 lung cancer cells (IC50 = 0.58 μM). CAI/II-IN-13 can be used for the study of lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
