1370032-19-1
Chemical Structure
CA-5f
- CAS 番号: 1370032-19-1
- Formula:C24H24N2O3
- Molecular Weight:388.46
IUPAC Name: (E)-3-((1H-indol-3-yl)methylene)-5-((E)-3,4-dimethoxybenzylidene)-1-methylpiperidin-4-one
InChIKey: JYOLPDWVAMBMQN-UBIAKTOFSA-N
SMILES: O=C(/C(CN(C)C/1)=C/C2=CNC3=C2C=CC=C3)C1=C\C4=CC=C(OC)C(OC)=C4
Biological Activity: CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity[1].
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CA-5f | 99.14% | CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity. | ||||||||||||||||||||
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Keywords