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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
ACE2 receptor
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "ACE2 receptor" in MCE Product Catalog:
30
30 Publications Verification
Synonyms: Ursodeoxycholate; Ursodiol; UDCA
3
3 Cited Publications
Cat. No.: HY-N0639
CAS No.: 65995-64-4
Category:
Punica granatum L. Phenols Polyphenols Punicaceae Plants Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Research Areas:
BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties .
Synonyms: Ursodeoxycholate-d4; Ursodiol-d4; UDCA-d4
Cat. No.: HY-P99344
CAS No.: 2423943-37-5
Synonyms: Anti-Human SARS-CoV-2; LY-3819253; LY-CoV555
Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard)
Target:
Research Areas:
SSAA09E2 is an inhibitor of SARS-CoV (Severe acute respiratory syndrome-Coronavirus) replication, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2) .
Cat. No.: HY-P99346
CAS No.: 2444308-95-4
Synonyms: CT-P59
Research Areas:
Cat. No.: HY-P5407
CAS No.: 798569-33-2
Cat. No.: HY-W342283
CAS No.: 536-71-0
Target:
Parasite Angiotensin-converting Enzyme (ACE) Angiotensin Receptor p38 MAPK STAT NF-κB TNF Receptor 5-HT Receptor
Research Areas:
Diminazene is an antiparasitic agent widely used to treat parasitic diseases caused by hemoparasites (such as trypanosomes and babesia). Diminazene acts as an ACE2 activator and exerts cardiovascular protective effects by activating the ACE2/Ang-(1-7)/Mas receptor axis. By regulating gut microbiota-tryptophan metabolism, Diminazene inhibits the activation of core inflammatory signaling pathways including MAPK, STAT and NF-κB, increases central 5-HT levels, and suppresses splenic TNF-α production, thereby alleviating systemic inflammation .
Cat. No.: HY-N12677
CAS No.: 199167-23-2
Synonyms: Caflanone; FBL-03G
Category:
Flavonoids Flavones Sesamum indicum Linn. Pedaliaceae Plants
Cat. No.: HY-175475
CAS No.: 1223950-00-2
Research Areas:
MolPort-010-778-422 is a high-affinity inhibitor targeting the ACE2 receptor of SARS-CoV-2 virus. MolPort-010-778-422 demonstrates excellent antiviral activity (IC50=8.9 nM). MolPort-010-778-422 is promising for research of SARS-CoV-2 .
Cat. No.: HY-N0639R
CAS No.: 65995-64-4
Category:
Cat. No.: HY-P991491
Target:
Research Areas:
Cat. No.: HY-175697
Research Areas:
Glycosyltransferase-IN-2 (Compound 20) is a Glycosyltransferase inhibitor. Glycosyltransferase-IN-2 has a broad-spectrum anticoronavirus activity with IC50s of 11.3, 5.5 and ~16.2 μM for MHV, HCoV-NL63 and SARS-CoV-2, respectively. Glycosyltransferase-IN-2 interferes with the coronavirus infectivity, alters viral protein glycosylation with inhibition of interaction with the ACE2 receptor or SC-VLP secretion, and inhibits RNA replication. Glycosyltransferase-IN-2 can be used for coronavirus infections research .
Cat. No.: HY-170767
SARS-CoV-2-IN-109 (compound 50) is an inhibitor targeting SARS-CoV with in vivo anti-infection activity. SARS-CoV-2-IN-109 targets the interaction between the SARS-CoV-2 Spike receptor-binding domain (RBD) and the human receptor angiotensin-converting enzyme 2 (ACE2) (EC50=26.5 μM), blocking the entry of SARS-CoV-2 into VeroE6 cells (EC50=17.0 μM). The CC50 of SARS-CoV-2-IN-109 for VeroE6 cells is >100 μM .
Cat. No.: HY-181066
Research Areas:
ACE2-SP PPI-IN-1 is an inhibitor of the interaction between the SARS-CoV-2 spike protein and ACE2, with an IC50 of 2162.77 nM. ACE2-SP PPI-IN-1 exhibits low cytotoxicity in human fibroblasts. ACE2-SP PPI-IN-1 binds to the interface region between the spike protein RBD and ACE2, reducing the flexibility of the critical receptor-binding loop and maintaining the structural compactness of the spike protein. ACE2-SP PPI-IN-1 can be used for research related to SARS-CoV-2 .
Cat. No.: HY-P990814
Cat. No.: HY-P990815
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
