SARS-CoV-2-IN-109
SARS-CoV-2-IN-109 (compound 50) is an inhibitor targeting SARS-CoV with in vivo anti-infection activity. SARS-CoV-2-IN-109 targets the interaction between the SARS-CoV-2 Spike receptor-binding domain (RBD) and the human receptor angiotensin-converting enzyme 2 (ACE2) (EC50=26.5 μM), blocking the entry of SARS-CoV-2 into VeroE6 cells (EC50=17.0 μM). The CC50 of SARS-CoV-2-IN-109 for VeroE6 cells is >100 μM.
For research use only. We do not sell to patients.
- Formula: C34H26N2O2
- Molecular Weight:494.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
SARS-CoV[1]
Chemical Information
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Molecular Weight 494.58
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Formula C34H26N2O2
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SMILES
[H][C@@]12C3=CC=CC=C3C=CN1[C@](C(C4=CC=CC=C4)=O)([H])[C@]5([H])C6=C(C=CC=C6)C=CN5[C@@]2([H])C(C7=CC=CC=C7)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)